KMID : 0882420150890060742
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Korean Journal of Medicine 2015 Volume.89 No. 6 p.742 ~ p.745
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Cryptococcal Meningoencephalitis in a Systemic Lupus Erythematosus Patient without Immunosuppressants
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Bae Soo-Ya
Oh Hyun-Ho Choi Seong-Jin Lee Jong-Ho Park Moon Han Seong-Hoon Kim Jeong-Yeon
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Abstract
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Cryptococcosis is an opportunistic infection that generally occurs in patients with cell mediated immune dysfunction and involves the central nervous system. Infection is a major cause of morbidity and mortality in systemic lupus erythematosus (SLE) patients because of its innate immune dysfunction along with the administration of steroids and immunosuppressants. However, central nervous system cryptococcosis has rarely been reported in SLE patients. A timely diagnosis is critical because of its significant mortality and morbidity. Most cases of cryptococcal meningitis in SLE patients have been reported in those treated with steroids or immunosuppressants. We report on a SLE patient not on medication, who was diagnosed with cryptococcal meningoencephalitis.
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KEYWORD
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Cryptococcosis, Meningitis, Cryptococcal, Lupus erythematosus, Systemic
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