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KMID : 0882420150890060742
Korean Journal of Medicine
2015 Volume.89 No. 6 p.742 ~ p.745
Cryptococcal Meningoencephalitis in a Systemic Lupus Erythematosus Patient without Immunosuppressants
Bae Soo-Ya

Oh Hyun-Ho
Choi Seong-Jin
Lee Jong-Ho
Park Moon
Han Seong-Hoon
Kim Jeong-Yeon
Abstract
Cryptococcosis is an opportunistic infection that generally occurs in patients with cell mediated immune dysfunction and involves the central nervous system. Infection is a major cause of morbidity and mortality in systemic lupus erythematosus (SLE) patients because of its innate immune dysfunction along with the administration of steroids and immunosuppressants. However, central nervous system cryptococcosis has rarely been reported in SLE patients. A timely diagnosis is critical because of its significant mortality and morbidity. Most cases of cryptococcal meningitis in SLE patients have been reported in those treated with steroids or immunosuppressants. We report on a SLE patient not on medication, who was diagnosed with cryptococcal meningoencephalitis.
KEYWORD
Cryptococcosis, Meningitis, Cryptococcal, Lupus erythematosus, Systemic
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